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Agonist/Antagonist Opioid Analgesics. When a client has Beforehand gained or is at this time undergoing a program of therapy with a pure opioid agonist analgesic like Dilaudid, agonist/antagonist analgesics like pentazocine, nalbuphine, butorphanol, and buprenorphine, really should be used with caution.Dilaudid (hydromorphone) is a robust opioid